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KMID : 1138720210470040057
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Korean Public Health Research
2021 Volume.47 No. 4 p.57 ~ p.65
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Relationship between Serum Folate Concentration and Dental Caries in Korean Adults
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Lee Sung-Hee
Park Sang-Shin
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Abstract
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Purpose: The purpose of this study was to examine the relationship between serum folate concentration and dental caries. Previous studies have shown a link between folate and some oral health, but the relationship between folate and permanent dental caries has yet to be established.
Methods: Our study population was 4,493 adults in the Korean National Health and Nutrition Examination Survey 2016-2018. To determine the status of dental caries relative to serum folate concentration, folate was divided into quintiles. We performed multiple linear and logistic regressions for the number of dental caries and prevalence of dental caries, respectively.
Results: The average age of participants was 49.5 years old, and their prevalence of dental caries was 28.7%. After covariate adjustments, the odds of participants in the 1st (lowest) and 2nd quintiles were 44% and 38% higher than that of the 5th quintile, respectively (P for trend = 0.015). Additionally, the prevalence of dental caries in the 1st to 5th quintiles was 32.1%, 30.9%, 30.5%, 29.5%, and 25.5%, indicating that the prevalence of dental caries decreased as the concentration of folate increased (P for trend = 0.016). An increase in serum folate was also associated with a decrease in the number of dental caries (B = ?0.047 ±0.02 and P value = 0.007). The average number of dental caries was found to be inversely proportional to the serum folate concentration.
Conclusions: Serum folate concentration in Korean adults was negatively related to the prevalence and number of dental caries.
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KEYWORD
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Folate, Dental caries, Oral health, Prevalence
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